![]() In-person collection processes carry an increased risk of infection due to potential exposure to a confluence of contagious individuals and consumes large quantities of valuable personal protective equipment (PPE). The in-person collection process is labor intensive, driving up testing costs and diverting healthcare resources from the care of ill individuals. The need for in-person collection limits access to testing for individuals who may not be able to get to a testing center due to distance, disability or inconvenience. Serological assays are important for assessing asymptomatic infection in close contacts, identifying individuals with resolved infection as potential contributors of convalescent plasma therapy, enabling estimation of population infection prevalence and illuminating our understanding of contributing factors conferring immunity to re-infection.Īll currently approved serological tests require blood specimens collected in-person by a healthcare worker either through phlebotomy or finger-prick. While direct detection of the virus by RNA or antigen assays remains the standard for confirming acute SARS-CoV-2 infection, serological antibody testing is of increasing importance for many reasons 4, 5, 6, 7, 8. At the time of writing, SARS-CoV-2 pandemic has led to more than 35 million confirmed cases globally and claimed approximately 1 million lives as of Oct 6th, 2020. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), formerly known as 2019-nCoV, is an enveloped, single-stranded RNA virus in the family Coronaviridae, genus Betacoronavirus 1, 2, 3.
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